A Seoul-Fluor-based bioprobe for lipid droplets and its application in image-based high throughput screening.
نویسندگان
چکیده
We developed a novel fluorescent bioprobe (SF44) that can specifically visualize the cellular lipid droplets in in vitro and in vivo systems and illustrated the mechanistic rationale of its fluorogenic property. Its application to image-based high throughput screening led us to the identification of a new small-molecule modulator of lipid droplet formation.
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عنوان ژورنال:
- Chemical communications
دوره 48 17 شماره
صفحات -
تاریخ انتشار 2012